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US 2019/0106400 A1Published application
Process For Preparing Pleuromutilin
AssigneeCalifornia Institute of Technology
InventorsElliot P. Farney, Sean S. Feng, Sarah Reisman
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Abstract
The present disclosure provides processes for preparing (+)-pleuromutilin and synthetic (+)-pleuromutilin produced therefrom. Also provided are intermediates prepared thereby and processes for preparing these intermediates.
Claims27
A process comprising:
- contacting a compound of Formula I
- with samarium(II) iodide
- in an organic solvent;
- for a time and under conditions effective to produce a compound of Formula II
- wherein R1 is H or an oxygen protecting group.
2 more elements
A compound that is:
Dependencies are inferred from the claim text.