Image simulation system to covisualize electrodes and cortical vessels on 3d brain and its method

An image simulation method to covisualize electrodes and cortical vessels on three dimensional (3D) brain structure diagram, comprising:

• installing a first image capturing device in a step of capturing a plurality of first Images to capture a plurality of first images of a brain in advance, wherein the plurality of first images are completely used to display a three-dimensional structure of the brain;
• installing a second image capturing device in a step of capturing a plurality of second Images to capture a plurality of second images of the brain in advance, wherein the plurality of second images are completely used to display blood vessels of the brain;
• installing a third image capturing device in a step of capturing a plurality of third Images to capture a plurality of third images of the brain after the brain is implanted with at least one electrode, wherein the plurality of third images are completely used to display the at least one electrode in the brain;
• retrieving the plurality of second images as standards in a step of image alignment, and retrieving correspondingly a plurality of first images for image adjustment and alignment so as to generate a plurality of aligned first images via respectively matching a head contour in the plurality of second images;
• simultaneously retrieving the plurality of second images as standards, and retrieving correspondingly a plurality of third images for image adjustment and alignment so as to generate a plurality of aligned third images via respectively matching the head contour in the plurality of second images;
• enhancing contrast between each of the blood vessels and its adjacent non-vessel portions shown in the plurality of retrieved second images via image processing in a step of coloring to visualize the each blood vessel, and coloring the each blood vessel with a first color to visualize a location of the each blood vessel at the brain in the plurality of retrieved second images;
• simultaneously enhancing contrast between the at least one electrode and its adjacent non-electrode portions shown in the plurality of aligned third images via image processing to visualize the at least one electrode, and coloring the at least one electrode with a second color to visualize a location of the at least one electrode at the brain in the plurality of aligned third images;
• and
• integrating the plurality of aligned first images, the plurality of colored second images and the plurality of colored third images in a step of integrating to obtain integrated viewable information of the brain, the at least one electrode and the blood vessels for medical reference.