Beta lactamase as biomarker for the specific detection of tuberculosis-complex bacteria
AssigneeThe Texas A&M University System
InventorsJeffrey D. Cirillo, Michael T. Norman
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Abstract
The present disclosure provides methods, reagents, systems, and devices that target β lactamase as a biomarker for the sensitive and specific detection of tuberculosis-complex bacteria. Specifically, the present disclosure relates to methods and compositions for the detection of specific β-lactamase protein and nucleic acid sequences to indicate the presence of tuberculosis-complex bacteria.
Claims16
A method of detecting the presence of tuberculosis-complex bacteria in a biological sample obtained from a subject, the method comprising determining the presence or amount of anti-β-lactamase (BlaC) antibody in the biological sample, wherein the presence or amount of anti-BlaC antibody in the biological sample is indicative of the presence of tuberculosis-complex bacteria in the subject.
Dependencies are inferred from the claim text.