Fully-automated biological slide specimen processing device and method
AssigneeXiamen Talent Biomedical Technology Company, Ltd.
InventorsJames GUO, Derek GUO
Life of this patent
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Abstract
A fully-automated biological slide specimen processing device and a method. The device mainly includes a testing assembly, a base platform, a Z-arm, an X-arm, a Y-arm, a dispensing nozzle and scanning devices for identifying a reagent and a specimen. The device in the present invention can automatically realize regular and quantitative dispensing according to testing process requirements and testing steps, automatically control the heating, automatically control liquid filling and liquid discharging, and realize full automation of the testing process. When the slide specimen needs a heat treatment, an insertion slot may be directly filled with liquid and be heated.
Claims17
A fully-automated biological slide specimen processing device, wherein the device comprising:
- a testing assembly;
- a base platform;
- a Z-arm;
- an X-arm;
- a Y-arm;
- a dispensing nozzle;
- a reagent scanner which can identify a barcode and a QR code of the reagent;
- and a slide specimen scanner which can identify a barcode and a QR code of the slide specimen, wherein X, Y and Z correspond to coordinate axes of the space rectangular coordinate system;
- wherein the testing assembly comprises a container, a base, a heating device, a liquid inlet, a liquid outlet, a controller, a thermocouple, a slide, a slide cover plate and a slide rack, the controller controls the heating device to start and to stop heating, the heating device is located above the base and below the container, the container is used for containing a heating medium and one or more slide racks, the thermocouple is placed inside the container, the thermocouple performs a real-time sense on a temperature in the container and transmits a sensed data to the controller, the controller adjusts a heating power output according to the sensed data, and the reagent scanner and the slide specimen scanner are each connected with the controller and transmit the scanned results to the controller,
- wherein the slide cover plate fits with the slide to assemble a set of slide assembly for specimen processing, two ends of the slide rack are hung on two lateral sides facing toward each other of the container, a gap is provided between a bottom end of the slide assembly in the slide rack and a bottom of the container,
- wherein the slide rack is provided with a plurality of integrated V-shape insertion slots which are upright or inclined, a spring piece is fixed inside each of the plurality of V-shape insertion slots, the plurality of V-shape insertion slots are arranged in one column closely, and the slide rack comprises one or more columns of the plurality of V-shape insertion slots, the slide assembly is inserted along the plurality of V-shape insertion slot of the slide rack, and a spring pressure generated by that a surface of the slide cover plate presses a plate-type spring is applied on the slide assembly to achieve a clamping function, and two ends of the slide rack are hung on two lateral sides facing toward each other of the container, so that the gap is provided between the bottom end of the slide assembly in the slide rack and the bottom of the container,
- wherein the Z-arm is upright fixed on the base platform, the X-arm is mounted on the Z-arm, the Z-arm is provided with a stepper control mechanism thereon for controlling the X-arm to move vertically along the Z-arm, the Y-arm is mounted on the X-arm, and the X-arm is provided with a stepper control mechanism thereon for controlling the Y-arm to move horizontally along the X-arm,
- wherein one dispensing nozzle or a plurality of dispensing nozzles are mounted on the Y-arm to form a dispensing nozzle set, the Y-arm is provided with a stepper control mechanism which is able to drive the dispensing nozzle set to move along the Y-arm under the control of the controller, the Y-arm is further provided with a spacing adjustment mechanism which is able to adjust a spacing between each dispensing nozzle of the dispensing nozzle set under the control of the controller, under the control of the stepper control mechanisms, the dispensing nozzle is able to move vertically to adjust an altitude of the dispensing nozzle, that is, a distance from the base platform, and the dispensing nozzle is able to automatically move to the above of a reagent loading reservoir of the slide assembly under the control of the stepper control mechanisms.
Dependencies are inferred from the claim text.