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AssigneeDsm IP Assets B.V.
InventorsJames G. METZ, Jerry M. KUNER, David Glen MCCASKILL, Mendy Louise FOSTER
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Factors For the Production and Accumulation of Polyunsaturated Fatty Acids (PUFAs) Derived from PUFA Synthases Abstract Disclosed are novel enhancing factor proteins of the PUFA synthase systems, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and recombinant host cells comprising such nucleic acid molecules, genetically modified microorganisms comprising the same, and methods of making and using the same. Also disclosed are genetically modified microorganisms that have been genetically modified to express a PUFA synthase system for the production of PUFAs, wherein the microorganisms have been modified to express the novel enhancing factor proteins of the PUFA synthase system.
1-48. (canceled)
A heterologous nucleic acid molecule comprising a nucleic acid sequence encoding a polypeptide that is at least 90% identical to the amino acid sequence of SEQ ID NO:2, wherein the polypeptide enhances polyunsaturated fatty acids (PUFA) production in a host cell compared to the PUFA production in a same host cell without the polypeptide.
Dependencies are inferred from the claim text.