Peptide with anti-obesity and anti-diabetic efficacy and use thereof

Abstract

The present invention provides a peptide with an anti-obesity and/or anti-diabetic activity consisting of an amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 2. The peptide of the present invention exhibits an excellent anti-obesity effect by inhibiting fat accumulation, reducing the sizes of adipocytes, and breaking down accumulated fat through an increase in the expression of lipolytic factors pHSL and AMPK-α1, and CGI-58, and furthermore, an excellent effect on diabetes by increasing an expression of adiponectin and AMPK which effectively reduce blood glucose and improves insulin resistance, increasing the expression of glucose transporter GLUT4, and increasing an expression of IRS-1, an insulin receptor signal transduction protein. The peptide of the present invention can be effectively used for the prevention or treatment of obesity and/or diabetes.

Dependencies are inferred from the claim text.