Inhibitors of bruton's tyrosine kinase
AssigneePharmacyclics, Inc.
InventorsWei Chen, Zhaozhong J. Jia, William D. Thomas
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Abstract
Disclosed herein are reversible and irreversible inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are described, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Claims2
1-20. (canceled)
A compound, wherein the compound is (R)-3-(1-(4-tert-butylbenzoyl)piperidin-3-ylamino)-5-(4-(morpholine-4-carbonyl)phenylamino)-1,2,4-triazine-6-carboxamide.
Dependencies are inferred from the claim text.