Systems and Methods for Processing Large Volumes of Biological Fluid

A system for processing biological cell suspensions comprising a:

• a) a disposable fluid circuit including a separation device, a fluid flow path in flow communication with said separation device and one more fluid access devices for establishing fluid communication between said flow path and one or more containers of a biological cell suspensions;
• b) a reusable hardware unit comprising a separation device drive unit for receiving said separation device, an operator input and a controller coupled to said input, the controller configured:
• i. to receive a processing parameter comprising the total volume of biological cell suspension to be processed from one or more source containers;
• ii. to receive a processing parameter comprising the concentration of cells in said one or more source containers;
• iii. to calculate the number of draws from said one or more source containers and the volume of each said draw.