Method for producing antithrombotic coating material
AssigneeTerumo Kabushiki Kaisha
InventorTakao ANZAI
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Abstract
Provided is a method for producing an antithrombotic coating material in which a high molecular weight polymer can be obtained by a solution polymerization using a radical polymerization initiator. The above-mentioned task is achieved by a method for producing an antithrombotic coating material, including steps of: preparing a methanol solution containing a monomer represented by formula (1): wherein in formula (1), R1, R2, and R3 are the same as those described in the specification, respectively; adding a radical polymerization initiator having a 10-hour half-life temperature of 60° C. or less to the methanol solution to prepare a polymerization reaction liquid; and polymerizing the monomer.
Claims8
An antithrombotic coating material, comprising:
- polyalkoxyalkyl (meth)acrylate that contains a structural unit (A) represented by formula (2):
- wherein in formula (2), R1 represents a hydrogen atom or a methyl group, R2 represents an alkylene group having 1 to 4 carbon atoms, and R3 represents an alkyl group having 1 to 4 carbon atoms,
- wherein the polyalkoxyalkyl (meth)acrylate has a weight average molecular weight of 200,000 or more, and
- wherein the polyalkoxyalkyl (meth)acrylate is dissolved in methanol or a mixture comprising water and methanol.
Dependencies are inferred from the claim text.