Medical devices using coated polymers
AssigneeMedvet Science Pty. Ltd.
InventorsEli MOORE, Glen Leon BENVENISTE, Claudine Sharon BONDER, Nicolas Hans VOELCKER
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Abstract
The present disclosure relates to medical devices using coated polymers, methods for reducing platelet attachment and/or fouling associated with medical devices, and methods for coating polymers. Certain embodiments of the present disclosure provide a medical device comprising one or more polymeric materials coated with a hyperbranched polyglycerol.
Claims46
A medical device comprising one or more polymeric materials coated with a hyperbranched polyglycerol.
A polymeric medical device comprising one or more surfaces coated with a hyperbranched polyglycerol.
A raft comprising one or polymeric materials coated with a hyperbranched polyglycerol.
A stent comprising one or more polymeric materials coated with a hyperbranched polyglycerol.
A method of reducing platelet attachment, fouling, cell attachment, anastomotic hyperplasia, clotting and/or thrombosis associated with a medical device comprising one or more polymeric materials, the method comprising coating the one or more polymeric materials with a hyperbranched polyglycerol.
A method of coating a polymeric substrate with a hyperbranched polyglycerol, the method comprising polymerisation of glycidol monomers to form a hyperbranched polyglycerol on the polymeric substrate and thereby coating the polymeric substrate with the hyperbranched polyglycerol.
A method of forming a hyperbranched polyglycerol coating on a polymeric substrate, the method comprising exposing the polymeric substrate to polymerisation of glycidol monomers and thereby forming a hyperbranched polyglycerol coating on the polymeric substrate.
A method of producing a medical device with one or more of reduced platelet attachment, fouling, reduced cell attachment, reduced inflammatory cell attachment, reduced anastomotic hyperplasia, reduced clotting and/or reduced thrombosis, the method comprising using a hyperbranched polyglycerol coated polymeric material in the device to reduce platelet attachment, fouling, cell attachment, inflammatory cell attachment, anastomotic hyperplasia, clotting and/or thrombosis associated with the medical device.
A method of producing a polymeric medical device with one or more of reduced platelet attachment, reduced fouling, reduced cell attachment, reduced inflammatory cell attachment, reduced anastomotic hyperplasia reduced clotting and/or reduced thrombosis, the method comprising coating the polymeric material in the medical device with a hyperbranched polyglycerol.
Dependencies are inferred from the claim text.