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AssigneeKolon Life Science, Inc.
InventorsSujeong KIM, Heonsik CHOI, Kyoungbaek CHOI, Minjung KIM, Yejin KWON, Hyeonyoul LEE, Minju KIM, Daewook KIM, Jangjoon PARK, Yeomoon SIM
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A method for delivery of a therapeutic agent to a nervous tissue. In particular, a method of delivering a therapeutic agent to a nervous tissue protected by the brain-blood barrier or meninges is disclosed. The method for delivery allows delivery of a therapeutic agent to a nervous tissue with high efficiency. In addition, the delivery method of a therapeutic agent to a nervous tissue is safe since it has lower side effects such as nervous damage than a method of administering a therapeutic agent directly to a nervous tissue.
A method for delivery of a biological molecule to a nervous tissue, which comprises injecting the biological molecule into a space between the inside of an intervertebral foramen and the dura mater surrounding the spinal cord and spinal nerve.
A method for relieving or treating pain, comprising injecting a composition comprising a gene encoding glutamate decarboxylase (GAD), a gene encoding interleukin-10 (IL-10), or a gene encoding a combination of GAD and IL-10 into a space between the inside of an intervertebral foramen and the dura mater surrounding the spinal cord and spinal nerve.
Dependencies are inferred from the claim text.