Back to results
US 2019/0099495 A1Published application
Biodegradable drug delivery compositions
AssigneeMedincell
InventorGeorges GAUDRIAULT
Life of this patent
Estimating the term…
Abstract
A biodegradable drug delivery compositions comprising a triblock copolymer containing a polyester and a polyethylene glycol and a diblock copolymer containing a polyester and an end-capped polyethylene glycol, as well as a pharmaceutically active principle is disclosed.
Claims10
1-43. (canceled)
A syringe comprising a biodegradable drug delivery composition comprising
- (a) a biodegradable triblock copolymer having the formula:
- poly(lactic acid)v-poly(ethylene glycol), w, -poly(lactic acid)x. wherein v and x are the number of repeat units ranging from 24 to 682 and w is the number of repeat units ranging from 4 to 273 and v=x or v≠x;
- (b) a biodegradable diblock copolymer having the formula:
- methoxy poly(ethylene glycol)y-poly(lactic acid)z, wherein y and z are the number of repeat units, with y ranging from 3 to 45 and z ranging from 7 to 327, wherein the ratio of the biodegradable triblock copolymer of (a) and the biodegradable diblock copolymer of (b) is 1:3 to 1:8 or 1:1 to 1:19 or 3:2 to 1:19 in said biodegradable drug composition, which is insoluble in an aqueous environment;
- and
- (c) risperidone (Example 6)
3 more elements
A method of treating a condition which is responsive to risperidone which comprises administering to a patient in need thereof a biodegradable drug delivery composition comprising (a) a biodegradable triblock copolymer having the formula:
- poly(lactic acid)v-poly(ethylene glycol), w, -poly(lactic acid)x. wherein v and x are the number of repeat units ranging from 24 to 682 and w is the number of repeat units ranging from 4 to 273 and v=x or v≠x;
- (b) a biodegradable diblock copolymer having the formula:
- methoxy poly(ethylene glycol)y-poly(lactic acid)z, wherein y and z are the number of repeat units, with y ranging from 3 to 45 and z ranging from 7 to 327, wherein the ratio of the biodegradable triblock copolymer of (a) and the biodegradable diblock copolymer of (b) is 1:3 to 1:8 or 1:1 to 1:19 or 3:2 to 1:19 in said biodegradable drug composition, which is insoluble in an aqueous environment;
- and (c) risperidone.
1 more element
A drug implant comprising
- (a) a biodegradable triblock copolymer having the formula:
- poly(lactic acid)v-poly(ethylene glycol), w, -poly(lactic acid)x. wherein v and x are the number of repeat units ranging from 24 to 682 and w is the number of repeat units ranging from 4 to 273 and v=x or v≠x;
- (b) a biodegradable diblock copolymer having the formula:
- methoxy poly(ethylene glycol)y-poly(lactic acid)z, wherein y and z are the number of repeat units, with y ranging from 3 to 45 and z ranging from 7 to 327, wherein the ratio of the biodegradable triblock copolymer of (a) and the biodegradable diblock copolymer of (b) is 1:3 to 1:8 or 1:1 to 1:19 or 3:2 to 1:19;
- and
- (c) risperidone.
3 more elements
Dependencies are inferred from the claim text.