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US 2019/0099490 A1Published application
Apparatus and method for magnetic delivery of drugs deep into articular cartilage for osteoarthritis
AssigneeWeinberg Medical Physics LLC
InventorsIrving N. WEINBERG, Sahar JAFARI, Lamar Odell MAIR
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Abstract
Disclosed embodiments provide a tool and methodologies for delivering drugs into articular cartilage of a subject's body.
Claims22
An apparatus for delivering a plurality of drug-loaded magnetic particles to a substantial amount of an entire thickness of cartilage of a cartilaginous joint of a subject, the apparatus comprising:
- one or more coils disposed near to the cartilage and outside a body of the subject;
- at least one image-guidance component positioned in proximity to the subject's cartilage;
- and
- a controller coupled to the one or more coils and configured to control the one or more coils to generate an oscillating magnetic field,
- wherein the at least one image-guidance component provides imaging data that enables delivery of the plurality of drug-loaded magnetic particles to a substantial amount of the entire thickness of the cartilage of the subject's cartilaginous joint.
2 more elements
A method of delivering drugs to a subject's cartilaginous joint, the method comprising:
- administering a plurality of drug-loaded magnetic particles to the subject;
- and
- performing image-guided magnetic delivery of the one or more drug-loaded magnetic particles to the subject's cartilaginous joint by propelling the plurality of drug-loaded magnetic particles into a substantial amount of an entire thickness of cartilage of the cartilaginous joint of the subject at least in part by applying an oscillating magnetic field to the cartilage using one or more coils.
Dependencies are inferred from the claim text.