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US 2019/0099484 A1Published application
Influenza virus vaccines and uses thereof
AssigneeIcahn School of Medicine at Mount Sinai
InventorsAdolfo Garcia-Sastre, Peter Palese, Florian Krammer
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Abstract
Provided herein are chimeric influenza hemagglutinin (HA) polypeptides, compositions comprising the same, vaccines comprising the same, and methods of their use.
Claims32
A chimeric influenza virus hemagglutinin (HA) polypeptide comprising a stem domain of an HA from influenza virus A/California/4/2009 (H1N1) or A/California/4/2009 (H1N1)-like influenza virus HA and a globular head domain of an HA from an HA from influenza virus A/Vietnam/1203/2004 (H5) or an A/Vietnam/1203/2004 (H5)-like influenza virus HA.
-51. (canceled)
Dependencies are inferred from the claim text.