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US 2019/0099474 A1Published application
Long lasting effect of new botulinum toxin formulations
AssigneeMedy-Tox, Inc.
InventorsHyun Ho Jung, Gi Hyeok Yang, Hyun Jee Kim, Chang Hoon Rhee
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Abstract
The invention relates to the use of an animal-protein-free botulinum toxin composition to treat a disease, disorder or condition in a patient in need thereof whereby the animal-protein-free botulinum toxin composition exhibits a longer lasting effect in the patient compared to an animal-protein-containing botulinum toxin composition.
Claims9
A method to reduce frequency of treatment with botulinum toxin, comprising:
- providing an animal-protein free botulinum toxin composition for local administration by injection at a treatment site, wherein administration of a first therapeutically effective amount is separated by a time interval from administration of a second therapeutically effective amount, said time interval being greater than a time interval between first and second treatment of a therapeutically effective amount of an animal-protein containing botulinum toxin composition administered by injection at the treatment site.
A method to increase efficacy of botulinum toxin, comprising:
- providing an animal-protein free botulinum toxin composition for local administration by injection at a treatment site, wherein administration of a first therapeutically effective amount is separated by a time interval from administration of a second therapeutically effective amount, said time interval being greater than a time interval between first and second treatment of a therapeutically effective amount of an animal-protein containing botulinum toxin composition administered by injection at the treatment site.
A method of botulinum toxin treatment, comprising:
- providing an animal-protein free botulinum toxin composition for local administration at a treatment site, the composition comprising botulinum toxin, a polysorbate and methionine, wherein administration of a therapeutically effective amount of the composition alleviates a symptom in a patient for a period of time greater than that provided by administration of a therapeutically effective amount of an animal-protein containing botulinum toxin composition locally administered at the treatment site.
Dependencies are inferred from the claim text.