US 2019/0099442 A1Published application

Artificial Invaplex Formulated with Deacylated Lipopolysaccharide

AssigneeThe United States of America, as represented by the Secretary of the Army, on behalf of the Walter

InventorsRobert W. Kaminski, Kevin R. Turbyfill, Edwin V. Oaks, Kristen Clarkson

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Disclosed herein are artificial Invaplexes comprising deacylated lipopolysaccharides and methods of making and using thereof.

Dependent claims

An artificial Invaplex comprising one or more invasin proteins complexed with a deacylated lipopolysaccharide from a gram-negative bacterial strain.

Dependencies are inferred from the claim text.

A61K 31/739
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers,…:…
A61K 9/0019
Galenical forms characterised by the site of application: injectable compositions; Intramuscular, intravenous, arterial, subcutaneous…
A61K 38/16
Medicinal preparations containing peptides: peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61K 38/164
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from bacteria

From the US filing history. Foreign family members aren’t listed.

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