Compositions for the treatment of chronic vulval and perineal pain and symptoms and conditions associated therewith
AssigneeT&A Pharma Pty. Limited
InventorsThierry VANCAILLIE, Alan HEWITT
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Abstract
Provides herein are compositions for the treatment of chronic vulval or perineal pain, and of symptoms or conditions associated therewith, comprising an estrogen, optionally estriol, and a tricyclic antidepressant, optionally amitriptyline, formulated for topical, transdermal or transmucosal administration. Also provided are methods for the production of said compositions and to uses thereof in the treatment of chronic vulval or perineal pain, and of symptoms or conditions associated therewith.
Claims24
A composition for the treatment of chronic vulval or perineal pain or a symptom or condition associated therewith, the composition comprising an estrogen and a tricyclic antidepressant, wherein the composition is formulated for topical, transdermal or transmucosal administration.
A topical composition for the treatment of chronic vulval or perineal pain or a symptom or condition associated therewith, the composition comprising estriol and amitriptyline.
A method for the treatment of chronic vulval or perineal pain or a symptom or condition associated therewith, the method comprising topically administering to a female subject in need thereof a composition comprising estriol and amitriptyline.
Use of an estrogen and a tricyclic antidepressant for the manufacture of a composition for the treatment of chronic vulval or perineal pain or a symptom or condition associated therewith, wherein the composition is formulated for topical, transdermal or transmucosal administration.
Use of estriol and amitriptyline for the manufacture of a composition for the treatment of chronic vulval or perineal pain or a symptom or condition associated therewith, wherein the composition is formulated for topical administration.
Dependencies are inferred from the claim text.