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US 2019/0099388 A1Published application
Topical compositions and methods for making and using same
AssigneeSebela International Bermuda Limited
InventorsBhushan HARDAS, Donna DALTON, Petra SCHEPPLER, Anja BUCH, Peter BODERKE
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Abstract
The present invention relates to improved topical gel compositions comprising an active agent, and uses thereof.
Claims13
A gel composition for topical administration comprising:
- (i) naftifine or a pharmaceutically acceptable salt thereof, present in an amount of from about 0.5 wt % to about 4 wt %;
- (ii) a solvent comprising a glycol solvent component and an alkyl alcohol solvent component, present in an amount of from about 10 wt % to about 50 wt %;
- (iii) a hydroxy cellulose, present in an amount of from about 0.75 wt % to about 2.25 wt %;
- (iv) a polysorbate solubilizing agent present in an amount of from about 3 wt % to about 8 wt %;
- (v) an amine pH adjuster in an amount of from about 0.12 wt % to about 0.23 wt %;
- and
- one or more of:
- water, a preservative, a chelating agent, a coloring agent, and a fragrance.
5 more elements
Dependencies are inferred from the claim text.