Solid Oral Sulfate Salt Formulations For Cleaning A Colon And Methods Of Using Same
AssigneeBraintree Laboratories, Inc.
InventorsMark vB. Cleveland, Edmund V. Dennett, JR., Russell W. Pelham
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Abstract
Disclosed herein are solid oral dosage formulations comprising sodium sulfate, magnesium sulfate, and potassium chloride for inducing purgation of the colon of a subject. Furthermore, the disclosed compositions and formulations are useful to cleanse the colon when administered in sufficient quantities. Methods for inducing purgation of the colon and for cleansing the colon are also disclosed.
Claims45
-20. (canceled)
A solid oral dosage form comprising from about 0.6 grams to about 3.0 grams of sodium sulfate, from about 0.1 grams to about 0.6 grams of magnesium sulfate, and potassium chloride.
A method of cleansing a colon of a patient, the method comprising:
- a. administering a solid oral dosage form comprising an effective amount of sodium sulfate and magnesium sulfate to induce purgation of the colon, the solid oral dosage form further comprising an effective amount of potassium chloride when in combination with sodium sulfate and magnesium sulfate reduce clinically significant electrolyte shifts;
- and
- b. administering one or more volumes of a liquid,
- wherein the solid oral dosage form induces two or more purgations of the colon such that the colon is cleansed.
Dependencies are inferred from the claim text.