Buffered microencapsulated compositions and methods
AssigneePremier Dental Products Company
InventorsMark A. Latta, Stephen M. Gross, William A. McHale
Life of this patent
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Abstract
A microcapsule composition comprising at least one polymer substantially disposed as a semi-permeable shell around an aqueous buffered solution and at least one agent, wherein the agent permeates the shell, and wherein the composition is suitable for delivery to a mammal.
Claims28
A microcapsule formulation comprising a plurality of microcapsules and a carrier, each of said microcapsules having a semi-permeable shell formed of at least an amphiphilic polyurethane polymer having a molecular weight between 1,000 g/mol to 20,000 g/mol, and encapsulating therein a buffered solution and an additive, wherein said buffered solution is in contact with the semi-permeable shell, wherein the microcapsules are disposed within the carrier.
A method of manufacturing a microcapsule comprising:
- contacting an aqueous buffered solution comprising an additive to an oil phase, an amphiphilic polyurethane polymer having a molecular weight between 1,000 g/mol to 20,000 g/mol, and an emulsifying agent, forming a microcapsules through a surfactant-free inverse emulsion of water in oil, wherein the polymer substantially forms a semi-permeable shell around the aqueous buffered solution and said additive.
Dependencies are inferred from the claim text.