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US 2019/0099334 A1Published application
Buffered microencapsulated compositions and methods
AssigneePremier Dental Products Company
InventorsMark A. Latta, Stephen M. Gross, William A. McHale
Life of this patent
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Abstract
A microcapsule composition comprising at least one polymer substantially disposed as a semi-permeable shell around a buffered solution and at least one therapeutic agent, wherein the therapeutic agent permeates the shell, and wherein the composition is suitable for topical epithelial cells of mammal.
Claims28
A topical microcapsule composition comprising:
- a plurality of microcapsules and a carrier, each of said microcapsules comprising at least one polymer substantially disposed as a semi-permeable shell around a buffered solution, said microcapsule composition comprising at least a first subset of microcapsules, wherein a microcapsule within the first subset of microcapsules comprises a therapeutic agent for topical use on epithelial tissue;
- wherein the therapeutic agent permeates the shell.
A method of forming a topical microcapsule composition comprising a plurality of microcapsules:
- said plurality of microcapsules being formed by combining a polymer and at least one buffered aqueous solution comprising a therapeutic agent, by contacting:
- (a) said buffered solution comprising the therapeutic agent, (b) an oil phase, (c) said polymer, and (d) an emulsifying agent, wherein the polymer substantially forms a semi-permeable shell around the buffered aqueous solution;
- and adding said plurality of microcapsules to a carrier.
Dependencies are inferred from the claim text.