Vascular Valved Prosthesis and Manufacturing Method
AssigneesAssistance Publique-Hopitaux de Paris, Statice, Universite Paris Descartes
InventorsDavid Kalfa, Philippe Menasché, Pierre Pouponneau, Clément Leonard, Sébastien Perrot
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Abstract
The present invention relates to an electrospun fully biodegradable vascular valved prosthesis, allowing tissue regeneration and growth potential optionally comprising a bifurcation, preferably T-shaped, a mandrel for electrospinning said vascular valved prosthesis, and a method for electrospinning said vascular valved prosthesis.
Claims17
A fully biodegradable vascular valved prosthesis, comprising an electrospun inner conduit having a proximal end and a distal end and which is disposed within an electrospun outer conduit having a proximal end and a distal end, wherein the inner conduit is attached to the outer conduit such as to function as a valve allowing unidirectional flow of a fluid through said outer conduit from the outer conduit's proximal to distal end,
- wherein the proximal end of said inner conduit is attached circumferentially along the inside of the outer conduit towards the proximal end of the outer conduit to form a circumferential commissure;
- wherein the distal end of said inner conduit is attached to the inside of the outer conduit towards the distal end of said outer conduit to form focal commissures at one or more discrete positions, wherein the focal commissures may extend longitudinally from the distal end of the inner conduit towards the proximal end of the inner conduit.
A mandrel for electrospinning, comprising a cylindrical mandrel core, one or more fixation means, and two or more shell pieces;
- wherein
- said fixation means are configured for attaching said or more shell pieces on or to said mandrel core such as to form a cylindrical mandrel shell circumferentially encapsulating at least partly said mandrel core or a cylindrical mandrel shell affixed to said mandrel core;
- said mandrel core and/or said fixation means are configured for being slidably removable from said mandrel;
- and
- said two or more shell pieces are configured for collapsing radially inward upon mandrel core and/or fixation means removal from said mandrel.
(canceled)
Dependencies are inferred from the claim text.