Method of diagnosing arthritis or other joint degrading disease
AssigneeLynxon AB
InventorsNiclas KARLSSON, Chunsheng JIN, Sebastian KALAMAJSKI, Sarah Ann FLOWERS
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Abstract
The invention provides a method of diagnosing arthritis or other joint degrading disease in a subject which comprises determining whether there is a presence or increase of lubricin having a joint tissue posttranslational modification, in a blood sample from the subject, the presence or increase of the lubricin having the joint tissue posttranslational modification indicating arthritis or other joint degrading disease in the subject. The invention further provides a kit or protocol for detecting arthritis or other joint degrading disease by detecting lubricin, the lubricin comprising a joint tissue posttranslational modification.
Claims12
A method of diagnosing arthritis or other joint degrading disease in a subject, which method comprises determining whether there is a presence or increase of lubricin having a joint tissue posttranslational modification, in a blood sample from said subject, said presence or increase of said lubricin having said joint tissue posttranslational modification indicating arthritis or other joint degrading disease in said subject.
A kit or protocol for detecting arthritis or other joint degrading disease by detecting lubricin, said lubricin having a joint tissue posttranslational modification, said kit or protocol comprising a first agent adapted to detect said joint tissue posttranslational modification.
Dependencies are inferred from the claim text.