Devices and Methods for Biological Assay Sample Preparation and Delivery
AssigneeDiassess Inc.
InventorsFrank B. Myers, III, Wei Hsuan Ho, Debkishore Mitra, John Robert Waldeisen, Ivan Krastev Dimov, Ryan C. Griswold, Bruce Richardson
Life of this patent
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Abstract
Devices and methods for preparing and delivering biological assay samples are provided herein. Components of such devices include a sample receiving module within which a biological assay sample can be prepared and a cap, which when operatively coupled with the sample receiving module, pressurizes the module. These devices can be employed for subsequently delivering a biological assay sample.
Claims60
A biological assay sample preparation device, the device comprising:
- a. a sample receiving module comprising a fluid container, a preparation solution, and a first attachment element;
- and
- b. a cap removably coupleable to the sample receiving module and comprising:
- i. a pressurizing component;
- and
- ii. a second attachment element operatively coupleable with the first attachment element,
- wherein the pressurizing component extends into and pressurizes the sample receiving module upon operative coupling of the first attachment element to the second attachment element.
A method of delivering a biological assay sample, the method comprising:
- a. collecting a biological sample with a sample collector;
- b. inserting the sample collector into a sample receiving module of a sample preparation device, wherein inserting the sample collector comprises exposing the biological sample to a preparation solution to produce a prepared biological assay sample;
- c. operatively coupling a cap of the sample preparation device to the sample receiving module and thereby pressurizing the sample receiving module;
- and
- d. delivering the prepared biological assay sample by depressurizing the sample receiving module by flowing at least a portion of the prepared biological assay sample out of the sample receiving module.
A biological assay sample preparation device, the device comprising:
- a. a cap comprising a first chamber, a plunger comprising a piercing member, and a seal;
- and
- b. a sample receiving module which is operatively coupleable to the cap and comprises a second chamber,
- wherein when the sample receiving module is operatively coupled to the cap, advancing the plunger pierces the seal with the piercing member and places the first chamber in fluidic communication with the second chamber.
A method of preparing a biological assay sample, the method comprising:
- a. operatively coupling a cap and a sample receiving module of a biological assay sample preparation device, wherein the cap comprises a seal and a plunger comprising a piercing member;
- and
- b. advancing the plunger to pierce the seal with the piercing member and thereby placing the first chamber in fluidic communication with the second chamber and preparing the biological assay sample.
Dependencies are inferred from the claim text.