Filter device for capturing target cell and target cell collecting method using the same
AssigneeKorea Institute of Machinery & Materials
InventorsSunghwan CHANG, Jung Yup KIM, Hyoun-Hyang PARK, Yeong-Eun YOO
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Abstract
The present invention relates to a filter device for capturing a target cell and a target cell collecting method using the same. A filter substrate by which a target cell is captured is formed of an elastic material. When blood passes, the size of a lattice hole of the filter substrate by which the target cell is captured is reduced. When the blood completely passes, the size of the lattice hole of the filter substrate by which the target cell is captured is restored, so that a destruction rate of the target cell may be reduced and a collect rate of the target cell may be increased.
Claims14
A filter device for capturing a target cell, the filter device comprising:
- a filter substrate formed of an elastic material;
- and
- a plurality of lattice holes arranged in the filter substrate,
- wherein when a specimen including a target cell passes through the filter substrate, the filter substrate is elastically compressed in one of a direction in which the lattice holes are formed and a direction intersecting with the direction in which the lattice holes are formed, so that the size of the lattice holes is reduced.
A target cell collecting method using a filter device for capturing a target cell, the target cell collecting method comprising:
- positioning a filter substrate formed of an elastic material and having a plurality of lattice holes arranged in the filter substrate, to be in contact with one surface of the support substrate;
- reducing a size of the lattice holes by elastically compressing edges walls defining the lattice holes by applying a surface pressure to an entire surface of the filter substrate through a pressing portion;
- capturing a target cell by allowing a specimen including the target cell to pass through the lattice holes;
- when the specimen completely passes through the lattice holes, restoring the size of the lattice holes by elastically restoring edge walls of the lattice holes by releasing the surface pressure applied by the pressing portion;
- and
- collecting the target cell captured by the lattice holes.
Dependencies are inferred from the claim text.