Method for detecting disease
AssigneeThe Noguchi Institute
InventorsJin-ichi Inokuchi, Lucas Veillon
Life of this patent
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Abstract
The present invention is a method for detecting at least one disease selected from the group consisting of visceral fat accumulation, hyperglycemia, dyslipidemia, hypertension and atherosclerosis or a disease two or more of which are combined or detecting onset risk of these diseases, which comprises (a) a step of measuring a ganglioside GM3 in a blood sample derived from a subject, wherein the ganglioside GM3 has a structure represented by the following formula (1). [In the formula (1), R1 represents a glycan constituting the ganglioside GM3, and R2—C(═O)— represents a fatty acid residue having 16 or more and 24 or less carbon atoms which may have a double bond, and having an OH group as a substituent.]
Claims19
1-10. (canceled)
A method for detecting at least one disease selected from the group consisting of visceral fat accumulation, hyperglycemia, dyslipidemia, hypertension and atherosclerosis or a disease two or more of which are combined or detecting onset risk of these diseases, which comprises
- (a) a step of measuring a ganglioside GM3 in a blood sample derived from a subject,
- wherein the ganglioside GM3 has a structure represented by the following formula (1):
- wherein R1 represents a glycan constituting the ganglioside GM3, and R2—C(═O)— represents a fatty acid residue having 16 or more and 24 or less carbon atoms which may have a double bond, and having an OH group as a substituent.
A detection kit, for detecting at least one disease selected from the group consisting of visceral fat accumulation, hyperglycemia, dyslipidemia, hypertension and atherosclerosis or a disease two or more of which are combined, or onset risk of these diseases, which contains a ganglioside GM3 as a standard substance,
- wherein the ganglioside GM3 has a structure represented by the following formula (1):
- wherein R1 represents a glycan constituting the ganglioside GM3, and R2—C(═O)— represents a fatty acid residue having 16 or more and 24 or less carbon atoms which may have a double bond, and having an OH group as a substituent.
Dependencies are inferred from the claim text.