Back to results
US 2019/0056405 A1Published application
Amplifying rare cell surface markers
OwnerMartin L. Yamush, Tali Konryinventors
Life of this patent
Estimating the term…
Abstract
This invention relates generally to a microfluidic device for encapsulation, incubation, and analysis of cell surface markers or secreted molecules from a single cell.
Claims16
1-8. (canceled)
A system for detecting expression of a specific protein or peptide by individual cells of a population of cells, the system comprising:
- a fluid control device configured to divide a sample comprising the population of cells into subsamples, such that each subsample contains at most one of the population of cells and each subsample is encompassed a hydrophobic fluid;
- rolling circle amplification reagents for detection of the presence of the specific protein or peptide;
- and
- a device operable to detect the rolling circle amplification reagents in individual subsamples.
1 more element
A kit comprising:
- a fluid control device configured to divide a sample comprising the population of cells into subsamples, such that each subsample contains at most one of the population of cells and each subsample is encompassed a hydrophobic fluid;
- and
- rolling circle amplification reagents for detection of the presence of the specific protein or peptide.
Dependencies are inferred from the claim text.