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AssigneeSekisui Medical Co., Ltd.
InventorsKanako ITOU, Motoki MORITA, Keigo KOHNO
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The present invention addresses the problem of suppressing cross-reaction with antigenic components similar to an analyte, in immunochromatography, so as to reduce detection of similar antigens, and prevent measurement value errors and false positive reactions, while maintaining or improving the detection sensitivity for the analyte, and thereby allowing accurate determinations. In the present invention, when an antibody that specifically binds to the analyte and the analyte are reacted under conditions in which a buffer solution is used in a specific pH range, even if similar antigens are also present, cross-reactivity between the antibody and similar antigens is suppressed, and the analyte can be accurately detected.
A detection method using immunochromatography, comprising steps (A) to (C):
An immunochromatographic test strip comprising the following components (1) and (2):
An immunochromatographic detection kit comprising the following components (1) and (2):
A method of reducing cross-reaction between an analyte and a substance similar to the analyte, in a method of detecting an analyte in a sample using an immunochromatographic test strip,
A spreading solution for immunochromatography for detecting oncofetal fibronectin, the spreading solution comprising the following (1) and (2):
A specimen extraction solution for detecting oncofetal fibronectin, comprising a buffer solution of pH 5.0 to pH 6.7.
Dependencies are inferred from the claim text.