Amyloid beta oligomer detection method, amyloid beta oligomer detection device, and amyloid beta oligomer detection program

A device for detecting an amyloid β oligomer, comprising:

• an acquisition means for acquiring time-resolved fluorescence spectrum data of thioflavin T brought into contact with a test sample;
• a calculation means for calculating normalized spectra by normalizing respectively the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 from the acquired time-resolved fluorescence spectrum data;
• a comparison means for comparing the two normalized spectra;
• and
• a determination means for determining the presence or absence of an amyloid β oligomer in the test sample based on a comparison result,
• wherein t1<t2≤t3<t4.

A program for detecting an amyloid β oligomer arranged to make a computer function as:

• an acquisition means for acquiring time-resolved fluorescence spectrum data of thioflavin T brought into contact with a test sample;
• a calculation means for calculating normalized spectra by normalizing respectively the time-resolved fluorescence spectrum of time period t1 to t2 and the time-resolved fluorescence spectrum of time period t3 to t4 from the acquired time-resolved fluorescence spectrum data (with the proviso that, t1<t2≤t3<t4);
• a comparison means for comparing the two normalized spectra;
• and
• a determination means for determining the presence or absence of an amyloid β oligomer in the test sample based on a comparison result.