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US 2019/0055554 A1Published application
Compositions and methods for modulating hbv expression
AssigneeIonis Pharmaceuticals, Inc.
InventorsThazha P. Prakash, Punit P. Seth, Eric E. Swayze
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Abstract
Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.
Claims27
1-25. (canceled)
A compound comprising a modified oligonucleotide and a conjugate group, wherein the modified oligonucleotide consists of 16 linked nucleosides having a nucleobase sequence consisting of the nucleobase sequence of SEQ ID NO:
- 10, and wherein the conjugate group comprises:
Dependencies are inferred from the claim text.