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US 2019/0055288 A1Published application
Methods and products for genetic engineering
AssigneesInstitut National De La Sante Et De La Recherche Medicale (Inserm), Centre National de la Recherche Scientifique (CNRS), Ecole Normale Superieure De Lyon, Universite Claude Bernard Lyon 1
InventorsThéophile OHLMANN, Philippe MANGEOT, Emiliano RICCI
Life of this patent
Estimating the term…
Abstract
The present invention relates to a virus-derived particle comprising one or more Cas protein(s), as well as to kits and methods using the same for altering a target nucleic acid.
Claims21
A virus-derived particle comprising one or more Cas protein(s).
(canceled)
A kit for preparing virus-derived particles for altering a target nucleic acid in a eukaryotic cell comprising:
- a nucleic acid comprising an expression cassette encoding a GAG-Cas fusion protein, and
- a nucleic acid comprising one or more expression cassette(s) encoding virus-derived assembly protein(s).
15-20. (canceled)
A fusion protein comprising
- (i) a viral protein that self assembles, thereby generating a virus-derived particle, and
- (ii) a Cas protein.
Dependencies are inferred from the claim text.