Skin-penetrating peptide and method for using same
AssigneeIucf-Hyu (Industry-University Cooperation Foundation Hanyang University)
InventorsJe-Min CHOI, Wonju KIM, Ja-Hyun KOO, Jiyun KIM
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Abstract
The present disclosure is directed to providing a new skin-penetrating peptide, a fusion product with a biologically active substance bound using the same, a cosmetic composition containing the same and a pharmaceutical composition for external application to skin containing the same. The skin-penetrating peptide of the present disclosure is less likely to cause an immune response as compared to existing skin-penetrating peptides and exhibits remarkably improved skin permeability. Therefore, the biologically active substance can be effectively delivered through the skin, particularly through the stratum corneum.
Claims17
A skin-penetrating peptide having a sequence of (X1)n-X2-(cysteine)-(X3)m, wherein
- n is an integer from 3 to 14,
- m is an integer from 4 to 14,
- each of X1 and X3 is independently arginine, lysine or histidine, and
- X2 is alanine, glycine, proline, tryptophan, phenylalanine, leucine, isoleucine, methionine, valine, arginine, lysine or histidine.
Dependencies are inferred from the claim text.