Methods and compounds for treating paramyxoviridae virus infections
AssigneeGilead Sciences, Inc.
InventorsRichard L. Mackman, Jay P. Parrish, Adrian S. Ray, Dorothy Agnes Theodore
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Abstract
Provided are methods for treating Paramyxoviridae virus infections by administering ribosides, riboside phosphates and prodrugs thereof, of Formula I: wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Human parainfluenza and Human respiratory syncytial virus infections.
Claims13
(canceled)
A method of treating a Paramyxoviridae infection, comprising administering to a human subject in need thereof a therapeutically effective amount of a compound of Formula
- or a pharmaceutically acceptable salt or ester, thereof.
-14. (canceled)
-20. (canceled)
-30. (canceled)
A pharmaceutical composition comprising a therapeutically effective amount of a compound having a formula:
- or a pharmaceutically acceptable salt or ester thereof;
- and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.