US 2019/0054233 A1 · INFUSION SET WITH COMPONENTS COMPRISING A POLYMERIC SORBENT TO REDUCE THE CONCENTRATION OF M-CRESOL IN INSULIN

Abstract

An insulin infusion set (IIS) device with one or more features designed to achieve longevity in a patients continuous subcutaneous insulin infusion (CSII) site viability. One exemplary feature is an adsorbent material configured to adsorb phenolic excipients (e.g., m-cresol or other preservatives) from the insulin formulation. The adsorbent material may be positioned along a fluid pathway specifically designed to increase and/or extend exposure between the insulin formulation and the adsorbent material. Another exemplary feature is a medicament configured to reduce the patients inflammation or slow the progression of the patients inflammatory response. Yet another exemplary feature is a diffusive catheter configured to deliver the insulin formulation in a diffuse manner.

Claims22

Dependent claims

An insulin infusion set device comprising:

a flexible tubing configured to receive an insulin formulation containing at least one phenolic excipient;
a base coupled to the tubing and configured to receive the insulin formulation;
a catheter coupled to the base and configured to deliver the insulin formulation to a patient;
and
at least one polymeric sorbent material in fluid communication with the insulin formulation in the device, the at least one polymeric sorbent material being configured to collect the at least one phenolic excipient from the insulin formulation.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

16/094,628Filed 21 Apr 2017

Priority

22 Apr 2016

Published

21 Feb 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification15 codes

A61M 5/165
Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor: filtering accessories, e.g. blood filters, filters for infusion…
A61K 38/28
Hormones: insulins
A61M 5/14248
Adapted to be carried by the patient, e.g. portable on the body: of the skin patch type
B01J 20/262
Synthetic macromolecular compounds: obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by…

Infusion set with components comprising a polymeric sorbent to reduce the concentration of m-cresol in insulin

Life of this patent

Infusion set with components comprising a polymeric sorbent to reduce the concentration of m-cresol in insulin

Life of this patent

Abstract

Claims22