Compositions and methods for treatment of pediatric pain
AssigneeChildren's Hospital Medical Center
InventorsMichael P. Jankowski, Xiaohua Liu, John Barns Rose
Life of this patent
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Abstract
Disclosed are methods of treating pain in a mammal, which may include the step of administering human growth hormone to a mammal in need thereof. The pain treated by the disclosed methods may be of a type caused by inflammation induced mechanical and/or thermal hypersensitivity, and may include, for example, a pain type resulting from one or more conditions selected from peripheral injury pain, post-operative pain, cutaneous inflammation, cutaneous incision, muscle incision, or chronic pain. Disease states in which the disclosed methods may be used include fibromyalgia, sickle cell anemia, epidermolysis bullosa, erythromelalgia, complex regional pain syndrome, or generalized muscle pain.
Claims14
1-20. (canceled)
A method of preventing or treating pain in a subject, comprising the step of administering growth hormone to said subject immediately prior, during, or after a surgical event, wherein said administration is to a site of a cutaneous and/or muscular inflammation associated with said surgical event.
A kit comprising a composition comprising human growth hormone, and means for delivery of the composition to a human in need thereof.
An article of manufacture comprising:
- a. a container comprising a label;
- and
- b. a composition comprising growth hormone, wherein the label indicates that the composition is to be administered to a neonate, child, juvenile, or young adult, having, suspected of having, or at risk for developing, pain.
Dependencies are inferred from the claim text.