US 2019/0054112 A1Published application

Polynucleotide formulations for use in the treatment of renal diseases

AssigneeModerna Therapeutics, Inc.

InventorFrancine M. GREGOIRE

Life of this patent

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Abstract

The present invention relates to compositions and methods for the preparation, manufacture and therapeutic use of renal polynucleotides.

Claims45

Dependent claims

A pharmaceutical composition comprising at least one mRNA, said at least one mRNA encoding a renal polypeptide of interest, wherein said at least one mRNA is formulated in a lipid nanoparticle.

Dependencies are inferred from the claim text.

Facts

Application: 15/760,659Filed 16 Sep 2016
Priority: 18 Sep 2015
Published: 21 Feb 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification19 codes

A61K 31/7115
Compounds having three or more nucleosides or nucleotides: nucleic acids or oligonucleotides having modified bases, i.e. other than adenine,…
A61K 9/1271
Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant: non-conventional liposomes,…
A61K 38/17
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from animals; from humans
A61K 47/10
Containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides: alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene…

Family

Application62/220,282Us provisional application · filed 18 Sep 2015
US 2019/0054112 A1This patent

From the US filing history. Foreign family members aren’t listed.

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