Nitric oxide generating formulations and kits
AssigneeThe Regents of the University of Michigan
InventorsMark E. Meyerhoff, Gergely Lautner, Anant Balijepalli, Umadevi Sajjan, Hang Ren
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Abstract
An example of a nitric oxide generating formulation includes an S-nitrosothiol (RSNO) powder, a salt, and an additive. The additive is to control or accelerate a rate of release of nitric oxide (NO) from RSNO after the RSNO powder, the salt, and additive are dissolved into a liquid carrier. The nitric oxide generating formulation may be part of a kit that includes a container for dissolving the components into a liquid carrier. One of the kits may be used to prevent and/or treat sinonasal infections and another of the kits may be used to create antimicrobial lock solutions.
Claims25
A nitric oxide (NO) generating formulation, comprising:
- an S-nitrosothiol (RSNO) powder;
- a salt;
- and
- an additive to control or accelerate a rate of release of NO from RSNO after the RSNO powder, the salt, and the additive are dissolved into a liquid carrier.
A nitric oxide (NO) generating kit, comprising;
- a first powder composition including S-nitrosothiol (RSNO);
- a second powder composition including an additive to control or accelerate a rate of release of the NO from the RSNO;
- a salt present in the first powder composition or the second powder composition or a third powder composition;
- and
- a container for dissolving the first and second powder compositions into a liquid carrier.
Dependencies are inferred from the claim text.