Pericardial sealing member for prosthetic heart valve
AssigneeEdwards Lifesciences Corporation
InventorTamir S. Levi
Life of this patent
Estimating the term…
Abstract
In one embodiment, a delivery assembly can comprise an annular frame, a leaflet structure positioned within the frame and secured thereto, and an outer skirt positioned around an outer surface of the frame. The annular frame can comprise an inflow end and an outflow end and can be radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. The outer skirt can comprise pericardial tissue having a fibrous parietal layer defining a first surface of the outer skirt and a serous parietal layer defining a second surface of the outer skirt. The outer skirt can be positioned such that the first surface is facing away from the frame and the second surface is facing towards the frame.
Claims20
An implantable prosthetic valve comprising:
- an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration;
- a leaflet structure positioned within the frame and secured thereto;
- and
- an outer skirt positioned around an outer surface of the frame, wherein the outer skirt comprises pericardial tissue having a fibrous parietal layer defining a first surface of the outer skirt and a serous parietal layer defining a second surface of the outer skirt, and wherein the outer skirt is positioned such that the first surface is facing away from the frame and the second surface is facing towards the frame.
A method of manufacturing a prosthetic heart valve, comprising:
- providing a piece of pericardial tissue comprising a fibrous parietal layer and a serous parietal layer;
- reducing the thickness of the piece of pericardial tissue by removing a portion of the serous parietal layer, the fibrous parietal layer defining a first surface of the tissue and the serous parietal layer defining a second surface of the tissue;
- positioning the pericardial tissue around an outer surface of a frame of the prosthetic heart valve and securing it thereto such that the first surface is facing away from the frame and the second surface is facing towards the frame.
A method of implanting a prosthetic heart valve, comprising:
- inserting a distal end portion of a delivery apparatus and a prosthetic heart valve coupled to the distal end portion of the delivery apparatus into a patient's body, wherein the prosthetic valve comprises:
- an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration;
- a leaflet structure positioned within the frame and secured thereto;
- and
- an outer skirt positioned around an outer surface of the frame, wherein the outer skirt comprises pericardial tissue having a fibrous parietal layer defining an outer surface of the skirt and a serous parietal layer defining an inner surface of the skirt;
- positioning the prosthetic heart valve adjacent a native valve of the patient's heart;
- and
- radially expanding the prosthetic heart valve such that the fibrous parietal layer contacts the surrounding native tissue.
Dependencies are inferred from the claim text.