Increased production of ginsenosides through improvement of protein-folding machinery of yeast
AssigneeKorea Research Institute of Chemical Technology
InventorsSun-Chang Kim, Ju Young Lee, In Seung Jang, Seohyun Kim, Jong Geon Jegal
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Abstract
The present invention relates to recombinant yeast, in which the productivity of ginsenoside is enhanced by overexpressing CPR5, PDI1, or ERO1 in yeast having the productivity of ginsenosides; a method for preparing the yeast; and a method for producing ginsenosides using the yeast.
Claims14
Recombinant yeast for producing a ginsenoside or a precursor thereof, wherein the expression level of a protein involved in protein folding is enhanced relative to its endogenous expression level.
A method for preparing recombinant yeast with an enhanced productivity of ginsenosides, comprising increasing the expression level of a protein involved in protein folding in a ginsenoside-producing yeast strain relative to its endogenous expression level.
A method for preparing recombinant yeast with an enhanced productivity of ginsenoside precursors, comprising increasing the expression level of a protein involved in protein folding in a ginsenoside precursor-producing yeast strain relative to its endogenous expression level.
Dependencies are inferred from the claim text.