Chromatogram data processing method and device
AssigneeShimadzu Corporation
InventorAkira NODA
Life of this patent
Estimating the term…
Abstract
Wavelength spectrums of peaks detected on a chromatogram based on observation data to be processed are extracted to create a spectrum set in which the intensity values of the spectrums are normalized. One wavelength spectrum is selected from the set, and a vector of the wavelength spectrum at each point in time of measurement based on the observation data is projected so as to be perpendicular to the vector of the selected spectrum. The vectors of the wavelength spectrums in the set are also similarly projected. Consequently, the selected spectrum is erased from the set. The processes are repeated until the set does not include a spectrum, and the obtained signals are added. The signal resulting from the addition is a signal indicating the waveform shape of an unknown baseline.
Claims7
1-6. (canceled)
A chromatogram data processing method that processes three-dimensional chromatogram data collected for a sample to be measured and having a time axis, a signal intensity axis, and a third parameter axis, the chromatogram data processing method comprising:
- acquiring a spectrum corresponding to each of a plurality of peaks detected on a chromatogram created based on the three-dimensional chromatogram data to be processed, the spectrum indicating a relation between a third parameter value and a signal intensity value;
- and
- estimating step of estimating a waveform shape of a baseline chromatogram indicating a baseline in the chromatogram based on a time series signal, by projecting a multi-dimensional vector which is a vector representation of a spectrum at each of a plurality points in time of measurement based on the three-dimensional chromatogram data in a direction perpendicular to a vector of a vector representation of the spectrum obtained at the peak spectrum acquiring step, and calculating a magnitude of a projection vector obtained accordingly as the time series signal.
A chromatogram data processing device that processes three-dimensional chromatogram data collected for a sample to be measured and having a time axis, a signal intensity axis, and a third parameter axis, the chromatogram data processing device comprising:
- a peak spectrum acquisition unit configured to acquire a spectrum corresponding to each of a plurality of peaks detected on a chromatogram created based on the three-dimensional chromatogram data to be processed, the spectrum indicating a relation between a third parameter value and a signal intensity value;
- and
- a baseline chromatogram waveform estimation unit configured to estimate a waveform shape of a baseline chromatogram indicating a baseline in the chromatogram based on a time series signal, by projecting a multi-dimensional vector which is a vector representation of a spectrum at each of a plurality points in time of measurement based on the three-dimensional chromatogram data in a direction perpendicular to a vector of a vector representation of the spectrum obtained by the peak spectrum acquisition unit, and calculating a magnitude of a projection vector obtained accordingly as the time series signal.
Dependencies are inferred from the claim text.