Mycobacterium lysterase: a novel treatment for acne
AssigneesThe Regents of the University of California, University of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsRobert L. Modlin, Graham F. Hatfull, Dominique J. Bardeau, Anil K. Ojha
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Abstract
Certain aspects of the invention relate to methods for preventing or treating a skin condition in a subject, comprising administering a composition comprising a lysterase to the subject. Some aspects of the invention relate to pharmaceutical compositions comprising a lysterase. Some aspects of the invention relate to methods for producing a pharmaceutical composition, comprising expressing a lysterase in a recombinant cell and purifying the lysterase.
Claims27
A method for preventing or treating a skin condition in a subject, comprising administering a composition comprising a lysterase to the subject.
The method of any one of the preceding claims, wherein the skin condition is acne.
The method of any one of the preceding claims, wherein the lysterase is lysin B.
The method of any one of the preceding claims, wherein the lysterase is D29 lysterase or Bxb1 lysterase.
The method of any one of the preceding claims, wherein the composition comprises about 1 nM lysterase to about 1 mM lysterase.
The method of any one of the preceding claims, wherein the composition does not comprise a phage.
A pharmaceutical composition comprising a lysterase.
Dependencies are inferred from the claim text.