Filtration device with removable protective member
AssigneeBoston Scientific Scimed, Inc.
InventorsJOSHUA CLARK, GENE T. STORBECK, SHANNON SMITH KENWOOD, CHRISTOPHER A. BENNING, SEAN CURRAN, SARAH JEAN HEIGHTON
Life of this patent
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Abstract
A cell filtration assembly adapted to capture cells from a biological sample during centrifugation includes a filter support member including a sample well and a filter membrane that spans the sample well. In some cases, the filter support member and/or the filter membrane may be adapted to be sectioned. In some cases, a protective element may be disposed over at least a portion of the filter support member in order to protect the filter support member from tissue processing reagents during processing of the cells captured from the biological sample.
Claims20
A cell filtration assembly comprising:
- a filter support member including a sample well;
- a filter membrane extending across the sample well;
- the filter support member and/or the filter membrane configured to be sectioned;
- and
- a protective element disposed over at least a portion of the filter support member, the protective element configured to protect the filter support member from tissue processing reagents during processing of the cells captured from the biological sample.
A cell filtration assembly adapted to capture cells from a biological sample, the cell filtration assembly comprising:
- a sectionable base member;
- a sample well defined within the sectionable base member;
- a porous surface defining a lower portion of the sample well, the porous surface adapted to capture cells from the biological sample while permitting fluids to pass therethrough during centrifugation;
- and
- a protective polymeric coating disposed over at least a portion of the sectionable base member;
- wherein the protective polymeric coating protects the sectionable base member against tissue processing reagents;
- and
- wherein the protective polymer coating is sectionable.
A cell filtration assembly adapted to capture cells from a biological sample, the cell filtration assembly comprising:
- a sectionable base member;
- a sample well defined within the sectionable base member;
- a porous surface defining a lower portion of the sample well, the porous surface adapted to capture cells from the biological sample while permitting fluids to pass therethrough during centrifugation;
- and
- a protective shell disposed over at least a portion of the sectionable base member;
- wherein the protective shell protects the sectionable base member against tissue processing reagents;
- and
- wherein the protective shell is removable prior to sectioning the sectionable base member.
Dependencies are inferred from the claim text.