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US 2019/0002952 A1Published application
Compositions and methods for diagnosis of shock
AssigneeAnazyme
InventorJohn Rodenrys
Life of this patent
Estimating the term…
Abstract
Methods and kits for diagnosis and staging of shock, and especially non-septic shock are presented in which protease activities and/or volatile compounds are measured from a biological sample to so identify and/or stage shock.
Claims20
(canceled)
A method for detecting putrescine, cadaverine, or a combination thereof, in a human having septic shock or non-septic shock, the method comprising:
- (i) obtaining a breath sample from the human;
- (ii) applying the sample to a solid carrier or a liquid carrier;
- (iii) detecting putrescine, cadaverine, or a combination thereof, in the solid carrier or the liquid carrier by infrared spectroscopy, ultraviolet spectroscopy, or visible spectroscopy;
- thereby detecting putrescine, cadaverine, or the combination thereof in the human having septic shock or non-septic shock.
1 more element
A method for detecting a volatile organic amine compound in a human having a shock condition, the method comprising:
- (i) obtaining a breath sample from the human;
- (ii) applying the sample to a solid carrier or a liquid carrier;
- (iii) detecting the volatile organic amine compound in the solid carrier or the liquid carrier;
- thereby detecting the organic amine compound in the human having the shock condition.
1 more element
A method of treating a shock condition in a human in need thereof, the method comprising:
- (i) obtaining a breath sample from the human;
- (ii) applying the sample to a solid carrier or a liquid carrier;
- (iii) detecting a volatile organic amine compound in the solid carrier or the liquid carrier;
- and
- (iv) treating the human for the shock condition.
2 more elements
Dependencies are inferred from the claim text.