Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals
AssigneeTherio, LLC
InventorJohn L. CURTIS
Life of this patent
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Abstract
Methods and formulations for a simplified, single-injection method to induce and control the synchronous growth (superstimulation), and ovulation (superovulation) of multiple ovarian follicles in bovine, ovine, caprine, camelid and other female animals enabling the subsequent collection of (a) multiple oocytes when conducting in-vitro fertilization, or (b) multiple embryos when conducting multiple ovulation embryo transfer.
Claims25
A method of inducing superovulation in bovine, ovine, camelid and other female animals, the method comprising the steps of:
- administering a protein microsphere matrix having a diameter ranging from 50-70 microns to a bovine animal, the protein microsphere matrix including a controlled release agent,
- wherein the step of administering the protein microsphere matrix to the bovine animal is performed via a single administration, and
- wherein the protein microsphere matrix induces dominant follicle removal, superovulation and timed ovulation of matured follicle cohort in the bovine animal.
A drug formulation for inducing superovulation in bovine animals, the formulation comprising:
- a protein microsphere matrix having a diameter ranging from 50-70 microns to a bovine animal;
- a controlled release agent,
- wherein the drug formulation induces superovulation of a bovine animal when administered to the bovine animal.
Dependencies are inferred from the claim text.