Microfluidic centrifuge device and method for performing solution exchange and separation
OwnerPouya REZAI, Pouriya BAYATinventors
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Abstract
A microfluidic centrifuge device for solution exchange and separation. The device includes a curved fluidic channel, a first inlet and a second inlet in fluid communication with a proximal end of the curved fluid channel, and a first outlet and a second outlet in fluid communication with a distal end of the curved fluidic channel. The curved fluidic channel has dimensions sufficient to direct a first subset of the microparticles to the first outlet by Dean drag and a second subset of the microparticles to the second outlet by inertial force.
Claims16
A microfluidic centrifuge device for solution exchange and separation, the device comprising:
- a curved fluidic channel;
- a first inlet and a second inlet in fluid communication with the curved fluidic channel at a proximal end thereof, the first inlet configured to direct a first fluid containing one or more microparticles into the curved fluidic channel and the second inlet configured to direct a second fluid into the curved fluidic channel;
- and
- a first outlet and a second outlet in fluid communication with the curved fluidic channel at a distal end thereof, the curved fluidic channel having dimensions sufficient to direct a first subset of the microparticles to the first outlet by Dean drag and a second subset of the microparticles to the second outlet by inertial force.
A method for solution exchange and separation using a microfluidic centrifuge device comprising a curved fluidic channel in fluid communication with a first inlet and a second inlet at a proximal end thereof, and a first outlet and a second outlet at a distal end thereof, the method comprising:
- directing a first fluid containing one or more microparticles into the curved fluidic channel through the first inlet;
- directing a second fluid into the curved fluidic channel through the second inlet;
- directing a first subset of the microparticles to the first outlet by Dean drag;
- and
- directing a second subset of the microparticles to the second outlet by inertial force.
Dependencies are inferred from the claim text.