Use of whey protein micelles and polysaccharides for improving insulin profile
AssigneeNestec S.A.
InventorsChristophe Joseph Etienne Schmitt, Etienne Pouteau, Simina Florentina Popa Nita, Laurence Donato-Capel, Lionel Jean Rene Bovetto
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Abstract
The present invention relates to a composition comprising polysaccharides and whey protein micelles for use in the treatment or prevention of a disorder linked to an increase in plasma postprandial insulin in a subject. The invention relates also to the non-therapeutic use of a composition comprising polysaccharides and whey protein micelles to decrease plasma postprandial insulin concentration. A further aspect of the invention is a process for forming polysaccharide-whey protein micelle complexes.
Claims15
A method for use in the treatment or prevention of a disorder linked to an increase in plasma postprandial insulin in a subject in need of same comprising administering a composition comprising polysaccharides and whey protein micelles wherein the polysaccharides have a negative zeta potential at a pH value in the range 2.5 to 4.5, the weight ratio of whey protein micelles to polysaccharide is between 30:1 and 0.8:1, and the whey protein micelles are obtainable by adjusting the pH of a whey protein aqueous solution to a value between 3.0 and 8.0 and subjecting the aqueous solution to a temperature between 80 and 98° C.
A composition comprising:
- polysaccharides and whey protein micelles, wherein the polysaccharides have a negative zeta potential at a pH value in the range 2.5 to 4.5;
- the weight ratio of whey protein micelles to polysaccharide is between 30:1 and 0.8:1;
- and the whey protein micelles are obtainable by adjusting the pH of a whey protein aqueous solution to a value between 3.0 and 8.0 and subjecting the aqueous solution to a temperature between 80 and 98° C.
Process for forming polysaccharide-whey protein micelle complexes comprising the steps of:
- forming whey protein micelles by adjusting the pH of a whey protein aqueous solution to a value between 3.0 and 8.0 and subjecting the aqueous solution to a temperature between 80 and 98° C.;
- combining polysaccharides with an aqueous dispersion of whey protein micelles to form a composition comprising an aqueous dispersion of polysaccharides and whey protein micelles, wherein the polysaccharides have a negative zeta potential at a pH value in the range 2.5 to 4.5 and the weight ratio of whey protein micelles to polysaccharide is between 30:1 and 0.8:1;
- and
- if the pH of the composition comprising an aqueous dispersion of polysaccharides and whey protein micelles is not already between 2.5 and 4.5, then adjusting the pH of the composition to between 2.5 and 4.5 to form polysaccharide-whey protein micelle complexes.
Dependencies are inferred from the claim text.