# US 2018/0343857 A1 · Biosolubilizer

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- Number: US 2018/0343857 A1
- Document ID: US20180343857A1
- Status: Published application
- Kind: A1
- Application number: 16/041,897
- Filed: 2018-07-23
- Published: 2018-12-06
- Earliest claimed: 2012-06-06
- Assignees: Soliance
- Applicants: Soliance
- Inventors: Cédric ERNENWEIN; Romain REYNAUD; Arnaud GUILLERET; Lucie PODEVIN; Alexis RANNOU; Frédérique LAFOSSE
- Web page: https://patentgrep.com/patent/US20180343857A1

## CPC

- A01N 25/30: characterised by the surfactants
- A01N 57/20: containing acyclic or cycloaliphatic radicals
- A61K 8/602: {Glycosides, e.g. rutin}
- A61K 47/26: Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A61P 17/00: Drugs for dermatological disorders
- A61Q 5/00: Preparations for care of the hair
- A61Q 19/00: Preparations for care of the skin
- C11B 9/00: Essential oils; Perfumes
- C11D 1/662: {Carbohydrates or derivatives}
- C11D 3/221: {Mono, di- or trisaccharides or derivatives thereof}
- C11D 3/43: Solvents
- A61K 2800/49: Solubiliser, Solubilising system
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- C11B: PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES (drying-oils C09F)
- C11D: DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL

## Abstract

Composition containing at least one substance that is not water-soluble and is solubilised in a sophorolipid, and at least water, and use thereof for cleaning hard surfaces and laundry, for killing plants, for combating insect pests, for combating fungus and mould proliferation, for combating gastropods, for combating moss, algae and lichen proliferation, for the cosmetics industry and for skin and hair care.

## Claims

### Claim 1

Cosmetic composition comprising at least one substance that is not water-soluble and is solubilized by a sophorolipid agent and at least water, wherein the sophorolipid agent represents 0.1 to 90% of the mass of the composition, the substance that is not water-soluble represents 0.01 to 65% of the mass of the composition and water 1 to 99.89% of the mass of the composition.

### Claim 2 (depends on 1)

The cosmetic composition of claim 1, wherein the sophorolipids have the following general structures
wherein
R1 and R1′ are independently of one another saturated hydrocarbon chains or have one or more non-hydroxylated unsaturations or have one or more hydroxyl, linear or ramified groups with 1 to 21 carbon atoms,
R2 and R2′ are independently of one another a hydrogen atom or a saturated alkyl radical or have one or more non-hydroxylated unsaturations or have one or more hydroxyl, linear or ramified groups with 1 to 9 carbon atoms,
R3, R4, R3′ and R4′ are independently of one another a hydrogen atom or an acetyl group, and
R5 is in OCH3 or OH or O−M+ group, where M+ is a metal ion or an organic cation, in particular ammonium salts such as dimethylammonium, trimethylammonium, isopropylammonium, monoethanolammonium, biethanolammonium, triethanolammonium, diphosphonium or O(CH2)mCH3, with m being between 1 and 11.

### Claim 3 (depends on 2)

The cosmetic composition of claim 2, wherein the form (1), represents 5 to 65% of the total mass of sophorolipids.

### Claim 4 (depends on 1)

The cosmetic composition of claim 1, wherein the sophorolipid is produced by a method of fermentation and is used in raw form or as an extract from the fermentation process.

### Claim 5 (depends on 1)

The cosmetic composition of claim 1, wherein the substance that is not water-soluble is a perfume or an essential oil.

### Claim 6 (depends on 1)

The cosmetic composition of claim 1, wherein the substance that is not water-soluble is an active cosmetic.

### Claim 7 (depends on 1)

The cosmetic composition of claim 1, wherein the cosmetic composition is a skin or care composition.

### Claim 8

Method for solubilizing a substance that is not water-soluble, comprising the steps of
(i) adding the substance that is not water-soluble to a concentrated aqueous solution containing 100 to 10% by weight of solubilizing agent;
(ii) agitating at a temperature between 10 and 100° C. for 0.05 minutes to 300 minutes to obtain a pre-mixture;
(iii) adding other constituents to the pre-mixture during continuous agitation; and
(iv) adding the amount of water necessary or the remaining portion of water to obtain a clear solution;
wherein the solubilizing agent consists at least essentially of one or more sophorolipid.

### Claim 9 (depends on 8)

The method of claim 8, wherein no other surfactants or solvents are added.

### Claim 10 (depends on 8)

The method of claim 8, wherein the sophorolipid is produced by a method of fermentation and is used in raw form or as an extract from the fermentation process.

### Claim 11 (depends on 8)

The method of claim 8, wherein the sophorolipids have the following general structures
wherein
R1 and R1′ are independently of one another saturated hydrocarbon chains or have one or more non-hydroxylated unsaturations or have one or more hydroxyl, linear or ramified groups with 1 to 21 carbon atoms,
R2 and R2′ are independently of one another a hydrogen atom or a saturated alkyl radical or have one or more non-hydroxylated unsaturations or have one or more hydroxyl, linear or ramified groups with 1 to 9 carbon atoms,
R3, R4, R3′ and R4′ are independently of one another a hydrogen atom or an acetyl group, and
R5 is in OCH3 or OH or O−M+ group, where M+ is a metal ion or an organic cation, in particular ammonium salts such as dimethylammonium, trimethylammonium, isopropylammonium, monoethanolammonium, biethanolammonium, triethanolammonium, diphosphonium or O(cH2)mCH3, with m being between 1 and 11.

### Claim 12 (depends on 11)

The method of claim 11, wherein the form (1) represents 5 to 65% of the total mass of sophorolipids.

### Claim 13 (depends on 8)

The method of claim 8, wherein the substance that is not water-soluble is a perfume or an essential oil.

### Claim 14 (depends on 8)

The method of claim 8, wherein the substance that is not water-soluble is an active cosmetic.