Recombinant cell, method for producing recombinant cell, and method for producing organic compound
AssigneeSekisui Chemical Co., Ltd.
InventorsMasahiro FURUTANI, Norihide NISHIYAMA, Kazufumi KAWABATA
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AssigneeSekisui Chemical Co., Ltd.
InventorsMasahiro FURUTANI, Norihide NISHIYAMA, Kazufumi KAWABATA
Estimating the term…
A recombinant cell having a function of synthesizing acetyl-CoA from methyltetrahydrofolate, carbon monoxide, and CoA, including: a gene that expresses an exogenous NAD(P)H consumption pathway, the gene being expressed in the recombinant cell, wherein expression in at least one of endogenous NAD(P)H consumption pathways of the recombinant cell is down-regulated, and the endogenous NAD(P)H consumption pathway is different from the exogenous NAD(P)H consumption pathway, and the recombinant cell produces an organic compound having 4 or more carbon atoms from at least one selected from the group consisting of carbon monoxide and carbon dioxide via the exogenous NAD(P)H consumption pathway.
A recombinant cell having a function of synthesizing acetyl-CoA from methyltetrahydrofolate, carbon monoxide, and CoA, comprising:
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The recombinant cell according to claim 21, wherein a part or whole of an adhE1 gene and an adhE2 gene of a host cell that is a basis of the recombinant cell is deleted, and the gene cluster, instead of the adhE1 gene and the adhE2 gene, is incorporated in a genome by homologous recombination.
A method for manufacturing a recombinant cell, the method comprising:
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Dependencies are inferred from the claim text.