Biocompatible nanoparticle and use thereof
AssigneeKyungpook National University Industry-Academic Cooperation Foundation
InventorsJeongsoo Yoo, Woonghee Lee
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Abstract
The present invention relates to a biocompatible nanoparticle and a use thereof and, more specifically, to a biocompatible nanoparticle formed by irradiation an electron beam to an aqueous solution comprising at least one substance selected from the group consisting of a polysaccharide, a derivative thereof and a polyethylene glycol, thereby inducing inter-molecular cross-linking or intra-molecular cross-linking, and to a use of the biocompatible nanoparticle in a drug carrier, a contrast agent, a diagnostic agent or an intestinal adhesion prevention agent or for disease prevention and treatment.
Claims13
A biocompatible nanoparticle formed exclusively by inter-molecular crosslinking or intra-molecular crosslinking of at least one selected from the group consisting of a polysaccharide, a derivative thereof, and polyethylene glycol.
A method for preparing biocompatible nanoparticles, the method comprising:
- (a) adding, to water, at least one material selected from the group consisting of polysaccharides, derivatives thereof, and polyethylene glycol to prepare a solution;
- and (b) irradiating the solution prepared in step (a) with an electron beam to crosslink the material.
Dependencies are inferred from the claim text.