# US 2018/0322809 A1 · Bio-model comprising a fluid system and method of manufacturing a bio-model comprising a fluid system

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- Number: US 2018/0322809 A1
- Document ID: US20180322809A1
- Status: Published application
- Kind: A1
- Application number: 15/772,029
- Filed: 2016-10-28
- Published: 2018-11-08
- Earliest claimed: 2015-10-28
- Assignees: Universiti Malaya
- Applicants: Universiti Malaya
- Inventors: Vickneswaran A/L MATHANESWARAN; Zainal Ariff Bin ABDUL RAHMAN; Yuwaraj Kumar A/L BALAKRISHNAN; Su Tung TAN
- Web page: https://patentgrep.com/patent/US20180322809A1

## CPC

- G09B 23/303: {specially adapted to simulate circulation of bodily fluids}
- G09B 23/30: Anatomical models {(G09B23/281 - G09B23/288 take precedence)}
- G09B 23/34: with removable parts
- B29C 64/386: Data acquisition or data processing for additive manufacturing
- B29L 2031/40: Test specimens {; Models, e.g. model cars (mannequins B29L2031/7028); Probes}
- B33Y 10/00: Processes of additive manufacturing
- B33Y 80/00: Products made by additive manufacturing
- G09B 23/286: {for scanning or photography techniques, e.g. X-rays, ultrasonics}
- G09B: EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS (devices for psychotechnics or for testing reaction times A61B5/16; games, sports, amusements A63; projectors, projector screens G03B)
- B29C: SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING (making preforms B29B11/00; making laminated products by combining previously unconnected layers which become one product whose layers will remain together B32B37/00 - B32B41/00)
- B29L: INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B33Y: ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING

## Abstract

A bio-model for simulating a surgical procedure comprises a synthetic anatomical structure which has a cavity. A fluid system is coupled to the cavity. In one embodiment the fluid system allows fluid to be pressurized. In one embodiment, the fluid system allows fluid to flow through the cavity. The bio-model may be manufactured based on medical image data using three-dimensional printing.

## Claims

### Claim 1

A bio-model comprising
a synthetic anatomical structure defining at least one cavity, the at least one cavity having a fluid inlet; and
a fluid system comprising a tube coupled to the fluid and configured to allow a fluid in the at least one cavity to be pressurized.

### Claim 2 (depends on 1)

A bio-model according to claim 1, further comprising a synthetic skin layer, wherein the tube passes through the synthetic skin layer.

### Claim 3

A bio-model comprising
a synthetic anatomical structure defining at least one cavity, the at least one cavity having a fluid inlet and a fluid outlet; and
a fluid system comprising an inlet tube coupled to the fluid inlet; and an outlet tube coupled to the fluid outlet, the fluid system being configured to cause a fluid to flow through the cavity.

### Claim 4 (depends on 3)

A bio-model according to claim 3, further comprising a synthetic skin layer, wherein the inlet tube and the outlet tube pass through the synthetic skin layer.

### Claim 5 (depends on 1)

A three dimensional bio-model according to claim 1 configured to be insertable into a slot in a base piece.

### Claim 6 (depends on 1)

A three dimensional bio-model according to claim 1, comprising a base piece and an insert, the base piece defining a slot, the insert being configured to fit into the slot, the insert comprising the synthetic anatomical structure and the fluid system.

### Claim 7 (depends on 6)

A three dimensional bio-model according to claim 6, the surface of the base piece having contours and/or features selected to mimic an external anatomy.

### Claim 8

A method of manufacturing a three dimensional bio-model, the method comprising
receiving medical image data for an anatomical structure;
generating three dimensional model data for the anatomical structure from the medical image data;
adding three dimensional fluid system structure data to the three dimensional model data for the anatomical structure to provide bio-model structure data; and
three dimensional printing the bio model structure data.

### Claim 9 (depends on 8)

A method according to claim 8, wherein the medical image data is segmented medical image data comprising indications of parts of the anatomical structure.

### Claim 10 (depends on 8)

A method according to claim 8, wherein the three dimensional model data for the anatomical structure comprises an indication of at least one cavity and the three dimensional fluid system structure data comprises an indication of a tube coupled to the at least one cavity.

### Claim 11 (depends on 8)

A method according to claim 8, wherein the three dimensional model data for the anatomical structure comprises an indication of at least one cavity and the three dimensional fluid system structure data comprises an indication of a connector for a tube coupled to the at least one cavity.

### Claim 12 (depends on 11)

A method according to claim 11, further comprising connecting a tube to the connector after three dimensional printing the bio-model structure data.

### Claim 13 (depends on 8)

A method according to claim 8, wherein the bio-model structure data comprises structure data for a plurality of bio-model parts, and three dimensional printing the bio-model structure data comprises three dimensional printing each of the plurality of bio-model parts separately, the method further comprising assembling the bio-model parts to form the bio-model.

### Claim 14 (depends on 8)

A method according to claim 8, wherein the bio-model is configured to be insertable into a slot in a base piece.
